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Podcast

GlycanAge: Can glycans tell your biological age? Little-known molecules that can influence our health in a big way

It’s extremely important to quantify the state of our health, because the data provide ways to act upon and improve various aspects of health. This is why I track my HRV continuously and perform regular blood tests. Marina Martinic Kavur at Genos shares with us how measuring your glycans, specifically immunoglobulin G (IgG) glycans can provide an uniquely valuable and actionable insight into our biological age. 

Video – Watch the interview on video

Interview with Marina Martinic Kavur

Audio – Listen to the interview

https://kenkohacks.com/wp-content/uploads/2021/08/Marina.mp3
Interview with Marina Martinic Kavur

Timestamps
1:20 What are glycans?
4:20 What are immuno glycans? 
9:40 GlycanAge test
12:20 How can glycan estimate your biological age?
16:20 Interventions to improve biological age
21:00 How fast can GlycanAge-based biological age change?
29:30 How blood markers for inflammation, such as CRP, compare with IgG glycans?
39:00 Is a higher GlycanAge correlated with all-cause mortality?
41:50 What improves/worsens your GlycanAge?
47:00 Hormones’ impacts on GlycanAge; roles of estrogen
53:30 How and how much our genes affect glycans?
55:30 Does sleep affect GlycanAge?

Shownotes
Genos website: https://genos-glyco.com/
GlycanAge website: https://glycanage.com/
Use discount code “KENKOHACKS” at checkout to get 15 % off ! Limited-time offer expires

Categories
Podcast

Michael Lustgarten PhD. Scientist with a plan to conquer aging; how rigorous biomarker tracking can help us live longer

Dr. Lustgarten is a scientist at Human Nutrition Research Center on Aging at Tufts University with a mission to conquer aging through rigorous tracking of biomarkers. His Youtube videos, in which Dr. Lustgarten crunches scientific data in formats easily digestible by everyone and also provides his own biomarkers, are super educational and have inspired me personally in many ways. In our interview, we discuss his Youtube videos, his book Microbial Burden, his cutting-edge research on microbiome’s impacts on aging and much more! 

Video – Watch the interview on video

Audio – Listen to the interview

https://kenkohacks.com/wp-content/uploads/2021/07/Michael.mp3
Audio file

Timestamps

1:30 Dr. Lustgarten’s approaches to longevity; quantification through biomarkers
7:00 Dr. Lustgarten’s Youtube videos; health optimization and longevity
10:30 Reference values vs. optimal values; why you should focus on the latter
17:00 Dr. Lustgarten’s longevity strategies including dietary and exercise based approaches
20:00 Exercises’ impacts on maximum and average lifespans
21:40 Nutrition-dense food
33:40 How to optimize mineral intakes? “Small scales vs. big scales”
37:50 What’s adequate Vitamin K intake? RDA is not always optimal
38:55 Organ meats, carnivore diet
43:00 How to optimize mitochondrial health; exercise, fasting
48:00 Body’s water content (hydration); impacts of vegetables, muscle mass
51:07 Dr. Lustgarten’s book: Microbial Burden
57:56 Microbial metabolites
67:50 Exercises’ impacts on gut microbiome

Probiotics, prebiotics and bacterial metabolites
Optimal values and reference values for biomarkers

  
I cannot recommend highly enough Dr. Lustgarten’s videos on Youtube! They provide bite-sized takeaways for everyone that are based on solid sciences/measurements, whether you are a novice just getting started with biohacking or a seasoned biohacker. 

Dr. Lustgarten’s Youtube channel:  youtube.com/channel/UCT1UMLpZ_CrQ_8I431K0b-g (or search for Michael Lustgarten) 
Facebook: @mike.lustgarten 
Twitter: @mike_lustgarten 
Instagram: @conqueraging122
Microbial Burden on Amazon: amzn.to/2V5WhXR

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Article

How Does Autonomic Nervous System Affect Health?

If you’ve been following my blog, you may already know that I’m very keen on learning about and improving my HRV through a continuous HRV monitoring. Why focus on HRV, you may ask.

It seems intuitive that autonomic nervous system (ANS), that regulates body’s vital functions like breathing, temperature and digestion, affects the rest of our body. But in which ways does it affect the body’s overall health? Does low HRV (dominant sympathetic nervous system) affect the immune system and how? Keep reading, if you, like me, have ever wondered these questions.